Mifepristone in treating clinical discussion.docVIP

 PAGE \* MERGEFORMAT 8 Mifepristone in treating clinical discussion [Abstract] Objective To investigate the low-dose mifepristone clinical efficacy of treatment of uterine fibroids. Methods 36 patients were randomly selected symptomatic uterine fibroids were mifepristone 12.5mg, 1 day, even for 3 months. Results after treatment of uterine myoma and uterine volume were significantly reduced, mostly to correct the anemia, increased hemoglobin, mild side effects. some patients can be used as hysterectomy and myomectomy preoperative medication to reduce blood loss. Conclusion meters of non-Division ketone treatment of uterine fibroids has some clinical efficacy, less side effects, is a feasible method of conservative treatment. [Keywords:] mifepristone; uterine fibroids; progesterone Uterine fibroids are the most common female genital benign, occur in 30 to 50-year-old women of childbearing age, women of childbearing age lines leading to one of the main hysterectomy. Its etiology is unknown, recent studies have shown that progesterone in The formation has an important role in the growth [1,2]. Mifepristone is a derivative of norethisterone for the progesterone receptor antagonist. To investigate the progesterone antagonist treatment of uterine fibroids, the author uses clinical application of small doses of mifepristone, the results reported below. 1 Materials and Methods 1.1 General information on 36 patients for the February 2007 In October -2009 diagnosed uterine fibroids in our hospital willing to take mifepristone-treated patients, aged 30 to 52 years, average 40.8 years old. All the patients were confirmed by gynecological examination and color Doppler ultrasound examination confirmed the diagnosis. Patients have varying degrees of menorrhagia, dysmenorrhea, menstrual cycles, menstruation and pelvic mass, urinary frequency and other clinical manifestations. which 22 patients with varying degrees of anemia, were unintentional, lung, kidney contr