Mushroom polysaccharide chemical composition and pharmacological effect of.doc

 PAGE \* MERGEFORMAT 8 Mushroom polysaccharide chemical composition and pharmacological effect of [Abstract] Objective: To study the chemical composition of polysaccharides sum matsutake and its pharmacological effects. Methods: Matsutake more Polysaccharide research methods, and the separation of a series, such as ABMP  I, ABMP  II active ingredient. Results: As a unique biological response modifier, pine mushroom polysaccharide has significant immunomodulatory, anti-tumor, anti-fatigue, the antagonistic effect of cyclophosphamide-induced damage, anti-inflammatory effects, as well as protecting liver and so on. Conclusion: Based on the pharmacological effects of mushroom polysaccharide, the drug has great prospects for the development and utilization. [Keywords:] matsutake; polysaccharide; chemical composition; biological activity Matsutake (Agaricusblazei Murill) classification in fungi is Basidiomycotina, layer-mycetes, Agaricales, mushroom Branch, mushroom genus, originating in Brazil, also known as ‘Brazilian mushrooms’. Matsutake contains anti-tumor activity of polysaccharides is far higher than the fungus, was studied in 15 species of edible fungi with anti-tumor activity was ranked first in [1  4]. A chemical research Reference to flooding primarily for heat, acid formulation, enzyme formulations, ethanol precipitation, chromatography method. Phenol a sulfuric acid colorimetric assay for polysaccharide classical method [5]. Pei-Long Sun, etc. tiered alcohol precipitation, gel chromatography method for isolation of fruiting bodies of water extracts from the mushroom polysaccharide isolated homogeneous polysaccharide, and were named ABMP  I and ABMP  Ⅱ . UV detected ABM  I have UV absorption, its main chain structure of α  (1-6) pyran-type D  glucan, and contains a small amount of binding protein (1.5%), while the ABMP  II binding protein does not exist . 2 biological activity 2.1 The anti-tumor effect In recent years, fungal