N terminal brain natriuretic peptide testing for diagnosis of heart failure in elderly.doc

 PAGE \* MERGEFORMAT 13 N terminal brain natriuretic peptide testing for diagnosis of heart failure in elderly [Abstract] Objective To investigate the plasma N terminal brain natriuretic peptide (NT-pro BNP concentration in the diagnosis of heart failure and old age to determine the significance of cardiac function. Methods 152 patients with heart failure patients, excluding abnormal renal function (serum creatininegt; 176.8 mol / L), were measured by ELISA, plasma NT-pro BNP concentration. select 143 cases of elderly patients without heart failure as the control group. all the selected candidates for the chest X ray, ECG, and color Doppler measurement of cardiac left ventricular ejection fraction (LVEF), left ventricular end diastolic volume (LVEDV), left ventricular end systolic volume (LVESV), left ventricular end diastolic diameter (LVDD), interventricular septal thickness (VST), left ventricular posterior wall thickness (LVPWT ), mitral early diastolic and late diastolic peak velocity ratio (E: A). the results of the heart failure group of LVDD, LVEF, NT-pro BNP significantly different than the control group (P lt;0.05), plasma concentration of NT-pro BNP NYHA functional class was a positive correlation, log NT-pro BNP and LVEF was negatively correlated with E: A was negatively associated with the positive correlation between the cardiothoracic ratio. Conclusion plasma NT-pro BNP levels rise in the heart failure group high, can be made in patients with chronic congestive heart failure diagnosis. different degrees of congestive heart failure, the plasma NT-pro BNP levels are closely related with disease severity. NYHA l level in patients with NT-pro BNP levels, suggesting that plasma NT-pro BNP levels in the elderly congestive heart failure earlier diagnosis exists. [Keywords:] N terminal pro-brain natriuretic peptide in the original diagnosis of Chronic Heart Failure With the population aging, heart failure (CHF, referred to as heart failure