N N two-dimethylamino benzaldehyde1,3propylenediamine Cu () Synthesis crystal structure and antibacterial activity.doc

 PAGE \* MERGEFORMAT 8 N N two-dimethylamino benzaldehyde1,3propylenediamine Cu () Synthesis crystal structure and antibacterial activity Study: Dual Huang, Jiang Zhiqing, Wuyu Zhu, Hongyan Yan [Abstract] Objective To test the Schiff base and its metal complexes in the antibacterial activity. Methods Synthesis of Schiff base and its solution, metal complexes, measured by both nephelometry minimum inhibitory concentration (MIC). The results of Schiff base and The copper () complex of Pseudomonas aeruginosa, Escherichia coli and Staphylococcus aureus are inhibited. Conclusions dimethylamino benzaldehyde 1,3-diaminopropane Cu (), ability to meet the Antimicrobial the dimethylamino benzaldehyde 1,3-diaminopropane. [Keywords:] benzaldehydes; diamine; copper, Schiff Bases; crystallography Most of Schiff base compounds with biological activity, some compounds also have good resistance to the original micro-organisms and significant anticancer activity [13], transition element complexes of Schiff also has antibacterial, anti-cancer, anti-virus and other biological activity [4] . aromatic aldehyde diamine Schiff bases have been reported antibacterial activity [5]. In order to broaden its aromatic aldehyde diamine complex field of study to better understand the structure of these compounds and the antibacterial activity, the author Schiff bases of N, N ‘dimethylamino the double 1,3-diaminopropane Benzaldehyde and its copper () complexes, crystal structure and antibacterial activity. 1 Materials and methods 1.1 Materials 1.1.1 reagent methanol (Analytical Reagent, AR), 1,3-diaminopropane (98%), 4-dimethylamino benzaldehyde (99%), DMF (AR), NaOH (Chemically Pure), Mueller Hinton agar (China Inspection and Quarantine Institute, Beijing Land Bridge Technology Co., Ltd., batch number 070202), 028040MH broth (Guangdong Kay microbial loop, Ltd, batch number 200701031), gentamicin sulfate (Zhengzhou Zhuo Feng Pharmaceutical Plant, batch number 8,061,911), wa