Naloxone treatment of neonatal hypoxic ischemic encephalopathy 80 cases.doc

 PAGE \* MERGEFORMAT 5 Naloxone treatment of neonatal hypoxic ischemic encephalopathy 80 cases Hypoxic ischemic encephalopathy (HIE) in neonatal diseases account for a high percentage, it is caused by neonatal death and one of the main children’s disability With the development of perinatal medicine and neonatal intensive care unit of the establishment , HIE has significantly reduced mortality, but survivors with permanent brain dysfunction incidence remains high, so as to improve survival in children with quality of life in recent years in our hospital naloxone treatment of HIE, to good effect, are reported below. Object and method 1.1 General Information 80 cases of children with the Department in January 2000 - March 2003, admitted to hospital neonatal diagnosis of HIE in children, including 44 cases of boys, girls, 36 cases of premature delivery in 2 cases, more than full-term children, birth weight of 2.3kg ~ 4.0kg, 20 minutes after the youngest students, maximum 20 hours after birth. 80 patients were randomly divided into control group and observation group to observe the group of 36 patients in the control group of 44 patients, clinical efficacy . 1.2 diagnostic groups of children are in line with meeting held in Hangzhou in October 1996 revised lt;lt;hypoxic ischemic encephalopathy, and clinical diagnosis based on degree ofgt;gt; standard, which observe the group of 36 patients, mild in 8 cases, moderate 16 cases severe in 12 cases, the control group of 44 patients, mild in 8 cases, moderate in 21 cases, severe in 15 cases. compared the two groups showed no significant (Pgt; 0.05). 1.3 The treatment groups were using the same supportive care and symptomatic treatment, that is to maintain blood gas and pH values #8203;#8203;in the normal range, maintain good blood perfusion to maintain blood glucose at .0 ~ 7.5mmol / L, between control of seizures, increased intracranial symptoms of brainstem compression and the elimination