Natural taurine in spontaneously hypertensive rat brain extracellular fluid and energy metabolism in hippocampus of SOD activity and MDA content in.doc

 PAGE \* MERGEFORMAT 7 Natural taurine in spontaneously hypertensive rat brain extracellular fluid and energy metabolism in hippocampus of SOD activity and MDA content in Authors: Cao Bo, Wu Yan, Gao Xiumei, mei, HU Li-min [Abstract] Objective To study the natural bezoar for the spontaneously hypertensive rats (SHR) brain energy metabolism and extracellular SOD activity in hippocampus, MDA content in. Methods microdialysis technique to observe a single, after given different doses of bezoar, SHR brain extracellular fluid glucose (GLU), lactate (Lac), lactate / glucose (L / G), lactate / pyruvate (L / P) changes in and, at drugs taken after 8h in rat hippocampus measured SOD activity and MDA content. Results Bezoar significantly increased SHR brain extracellular GLU content of SHR significantly increased the SOD activity in the hippocampus and lower MDA content. Conclusion bezoar can significantly improve the SHR cerebral energy metabolism, protect brain tissue, and has anti-lipid peroxidation effect. [Keywords:] Energy Metabolism in micro-dialysis lipid peroxidation in spontaneously hypertensive rats Abstract: ObjectiveTo study the effect of natural ox gallstone on energy metabolism, activity of SOD and content of MDA in SHR brain.MethodsThe changes of glucose, lactic acid, L / G, L / P in SHR brain ECF were observed by advanced microdialysis technology after single administration of natural ox gallstone and the activity of SOD and content of MDA were measured in hippocampus at the 8h hour after administration.ResultsThe natural ox gallstone could increase the content of glucose significantly, improve the activity of SOD, reduce the content of MDA . ConclusionThe natural ox gallstone can improve energy metabolism, inhibit lipid peroxidation obviously, play a role of protection on brain. Keywords:: Enevgy metabolism; Microdiclysis; SHR; Lipid peroxidation Studies have shown that high blood pressure will eventually through a series of changes in blood flow