Narrow-band UVB phototherapy combined treatment of adult varicella valaciclovir efficacy.doc

 PAGE \* MERGEFORMAT 5 Narrow-band UVB phototherapy combined treatment of adult varicella valaciclovir efficacy [Keywords:] chickenpox; valaciclovir; UV; AM narrow band March 2008 ~ September 2009, the author uses a wavelength of 311 nm narrow-band ultraviolet B (NB UVB) irradiation combined with valaciclovir treatment of 21 adult patients with chickenpox, and achieved good effect, are as follows. 1 Clinical data 1.1 General information on 40 cases selected are all my out-patients, diagnostic criteria are in line with adult chicken pox: generalized skin lesions, duration within the 4 d before treatment and outside is not used oral antiviral drugs, not taking glucocorticoids the motivation, lung, liver, kidney and other organs and systemic diseases, no pregnancy and breast-feeding women, matt allergies. the 40 patients were randomly divided into two: the treatment group, 21 cases, 11 males and 10 females, mean age 23.6 years (18 to 42 years); the control group 19 cases, 10 males and 9 females, average age 22.4 years (18 to 38 years) .2 patients have varying degrees of fever, sore throat, general malaise and other symptoms , body temperature 37.6 ~ 39.0 .2 patients age, disease duration and no significant difference (Pgt; 0.05), comparable. 1.2 Treatment of skin treatment group UV100L ultraviolet treatment device (Waldmann, Germany Company), wavelength 311 nm, radiation intensity of 8.63 mW/cm2. According to the patient’s skin type, the initial treatment dose was 0.4 ~ 0.5 J/cm2, irradiation if No erythema reaction, and gradually increased by 10% to 20% of the radiation dose, irradiation every other day 1, 3 times for a course of treatment, irradiation, eye protection. the treatment group, while use of NB UVB irradiation given valaciclovir 300 mg, 2 times a day orally, sharing 7 d; the control group only received valaciclovir 300 mg, 2 times a day orally, sharing 7 d.2 patients were treated with topical mupirocin ointment to prevent infection; of