Neonatal endotoxin shock with DICs first aid.docVIP

 PAGE \* MERGEFORMAT 12 Neonatal endotoxin shock with DIC’s first aid [Keywords:] newborn, endotoxin shock, disseminated intravascular coagulation, first aid This paper introduces the newborn endotoxic shock with DIC in the pathogenesis, clinical features and first aid. Focus on first aid, designed to help physicians master the essentials of clinical front line to improve the success rate and reduce mortality. 1 Pathogenesis Neonatal sepsis in the majority of G-HAP caused by bacteria, often in the NICU in a long time because of medical intervention, their respiratory tract, gastrointestinal barrier mechanism for the destruction of endogenous G-tuberculosis drug resistance to sepsis caused by retrograde infection. → G-bacteria infection in an outbreak of large population of bacteria endotoxin release → ↑ → activation of complement, macrophage inflammatory activation → ↑ ↑ → #8203;#8203;→ microcirculation microvascular spasm, splanchnic vasodilation of blood stasis → organ → tissue blood supply, oxygen barriers for ↑ → → free radical generation of acid release ↑ ↑, ↑ ↑ → #8203;#8203;cytokine storm damage of vascular endothelial intravascular coagulation ↑ ↑ → #8203;#8203;↑ ↑, NK cells ↓ ↓ → systemic hypoxic-ischemic damage ↑ ↑, DIC sicker → body fluids, acid-base disorders and the further deterioration of energy metabolism → MODS → MSOF. Clinical features 2 Sudden listlessness, the reaction is low, the skin pattern, pale skin complexion, dark green gray or extremely pale limbs Jueleng, high fever or body temperature did not rise, shortness of breath, fast or slow heart rate, irregular heartbeat, low heart sound blunt, blood pressure decreased or disappeared, decreased urine output. auxiliary examination: suddenly found white blood cells, low platelet count, acid-base disorders, PaO2, and SO2 is low, high blood sugar or low blood sugar conditions are deteriorating. Clinical Emergency 3 3.1 The principle of expansion of correcting acid, anti