Nervous system damage caused by alcohol dependence in Progress.doc

 PAGE \* MERGEFORMAT 15 Nervous system damage caused by alcohol dependence in Progress Keywords:: alcohol nerve damage First, an overview of [1-3] Alcohol abuse and alcohol dependence on the damage to the nervous system is multifaceted, and its clinical manifestations can be broadly classified into three categories: ① acute alcohol poisoning; ② alcohol syndrome and related exceptions, such as tremors, delirium, etc.; ③ and long-term drinking alcohol and alcohol dependence-related exceptions, including the central nervous system lesions, peripheral neuropathy and autonomic neuropathy and so on. ③ This article focuses on the first part of the contents. Required to indicate that some of the performance of the classification is more difficult. Wernicke (1881) first observed a occurred in alcoholics in the triad: sudden disturbance of consciousness, ophthalmoplegia, and ataxia. Korsakoff (1887) describes some of the alcohol-dependent persons in other cognitive relatively complete cases, noticeable memory impairment. Future generations that is named after these two syndromes. At the same time, Maudesley (1879) noted that some alcohol-dependent persons with Alzheimer’s disease appears similar to a comprehensive cognitive impairment. After a long period of time, the above three kinds of alcohol dependence syndrome has become a classic description of damage to the nervous system. In addition, the tremor is common in patients with alcohol dependence symptoms of neurological damage, especially the hands and tongue tremor. Freund et al [1] confirmed that the long-term alcohol abuse (its standard for more than 80 g / d of pure alcohol, more than 10 years) allows the frontal lobe of the M-cholinergic receptor significantly reduced; they also confirmed that putamen Department choline receptor also decreased, while the benzodiazepine receptor  not been damaged. Histological study found that there is no shrinkage of the frontal lobe performance. Tip of ethanol is not