Nitrendipine combined irbesartan hydrochlorothiazide systolic hypertension in elderly patients of 68 cases.doc

 PAGE \* MERGEFORMAT 7 Nitrendipine combined irbesartan hydrochlorothiazide systolic hypertension in elderly patients of 68 cases [Keywords:] nitrendipine, irbesartan hydrochlorothiazide, the elderly, systolic hypertension Many large-scale clinical trials and epidemiological studies confirm: systolic blood pressure (SBP) is the increase of occurrence and prognosis of cardiovascular and cerebrovascular events more closely the factors of .2001, “ gt; Magazine published a survey of hypertension in elderly Framingham United States found that: nearly 80% of elderly patients with hypertension is systolic hypertension (ISH). In recent years, the development of hypertension in the WHO guidelines and guidelines for prevention and treatment of hypertension in China promotion, blood pressure, diastolic blood pressure control mode for the treatment of attention from the gradual shift of the systolic blood pressure and pulse pressure in hypertension control concerns. According to the existing clinical data, more than 60% of hypertensive patients need at least 2 or more antihypertensive drugs in combination therapy to achieve blood pressure control (1). In this paper, to our hospital on 180 patients with ISH patients, application of nitrendipine and by Lun Ping (irbesartan hydrochlorothiazide tablets antihypertensive treatment, the patients. 1 Materials and Methods 1.1 The selection and exclusion criteria Selected conditions: SBP 160 ~ 200 mmHg, diastolic blood pressure (DBP) 60 ~ 90 mmHg. Exclude secondary hypertension and severe liver, renal insufficiency, without calcium antagonists (CCB and angiotensin receptor blocker (ARB drugs and drugs hydrochlorothiazide contraindications. 1.2 General Information Options to our hospital from March 2006 to June 2007 meet diagnostic criteria for elderly patients with ISH 180 cases. Randomly assigned to nitrendipine group (A group of 52 patients, 34 males and 18 females, aged 60 to 81 (mean (71.8 + -11.2 years).