Non-invasive ventilation in chronic obstructive pulmonary disease with respiratory failure of patients.doc

 PAGE \* MERGEFORMAT 4 Non-invasive ventilation in chronic obstructive pulmonary disease with respiratory failure of patients [Keywords:] failure Chronic obstructive pulmonary disease (COPD) with respiratory failure in patients with normal use spasm, asthma, anti-infection and symptomatic treatment to relieve the clinical symptoms. In recent years, non-invasive ventilation (NIPPV) because without endotracheal intubation, fewer complications, ease of use, etc., has been widely used in COPD patients with respiratory failure. COPD patients with respiratory failure at the same time combined with non-invasive ventilation (NIPPV) can effectively increase the amount of alveolar ventilation, improve ventilation and ventilation function in patients, reducing respiratory muscle load, and thus can quickly relieve patients with clinical difficulty in breathing, to improve the arterial blood gas and prognosis. First reported in 1981, SULLIVAN, etc. with the nasal (facial) mask continuous positive airway pressure (CPAP) treatment of OSAS, 1989 Nian MEDURI such as first reported by non-invasive positive pressure mask ventilation, after treatment of acute respiratory failure, NIPPV to be clinically a wide range of applications, and has achieved good efficacy [1]. Acute exacerbation of COPD and respiratory failure in patients with the existence of respiratory muscle fatigue (mainly the diaphragm), because of increased airway resistance and intrinsic PEEP (PEEPi) increases the respiratory power. NIPPV by positive pressure ventilation (PSV) to help patients to overcome the airway resistance and offer the applied PEEP to offset intrinsic PEEP (PEEPi) caused by the increase in suction power, some or all of doing work to replace the breathing muscles, thereby reducing the inspiratory muscle load, so that fatigue of respiratory muscles (diaphragm) has been closed. And NIPPV using bi-level positive airway pressure ventilation, contribute to poor gas into the alveolar ventilation, i