Normotensive type 1 diabetic patients with serum tumor necrosis factor- correlation of pulse pressure.doc

Normotensive type 1 diabetic patients with serum tumor necrosis factor- correlation of pulse pressure [Abstract] Objective To determine the pulse pressure in patients with type 1 diabetes and serum levels of inflammatory cytokines, and explore their relationship. 112 determined the normal blood pressure, body mass index in patients with type 1 diabetes, WHR, systolic blood pressure, diastolic blood pressure , pulse pressure, mean arterial pressure, smoking no, alcohol intake, insulin dose, HbA1c, STNFR1, STNFR2, IL 6, CRP level. The results of the index is only 112 subjects and pulse pressure receptors of the TNF @ There were significant differences between (STNFR1 and PP: r = 0.215, P = 0.030, STNFR2 and PP: r = 0.238, P = 0.020). Conclusion normotensive patients with type 1 diabetes, TNF @ the activation level of correlation with pulse pressure , suggesting that TNF @ in patients with type 1 diabetes may be the pathogenesis of cardiovascular disease play a role. [Keywords:] Type 1 diabetes TNF @ PP STNFR1 STNFR2 In recent years, the study found that 30 patients with type 1 diabetes before the age of the patients suffering from cardiovascular disease more likely. TNF @, IL 6, CRP and other inflammatory cytokines in patients with type 1 diabetes have abnormal expression. In addition, with the Age increases the pulse pressure is a predictor of cardiovascular disease. This measured pulse pressure in patients with type 1 diabetes and serum levels of inflammatory cytokines concentration level of pulse pressure and serum inflammatory cells The relationship between factors in type 1 diabetes and its cardiovascular complications of significance. Subjects and Methods 1. Study Diagnostic criteria by WHO in 1998 confirmed normal blood pressure (lt;140/90 mmHg) in patients with type 1 diabetes, 112 cases, male 59, female 53 cases, aged 27.4 + -6.6 years old. Subjects had no cardiovascular disease, acute and chronic inflammation , infectious diseases, have n