Of diabetes on wound healing of fibroblast Progress.docVIP

 PAGE \* MERGEFORMAT 13 Of diabetes on wound healing of fibroblast Progress [Abstract] Wound healing is a complex biological process is inflammatory cells and repair cells, extracellular matrix and cytokines and other factors involved and the high degree of coordination, the complex process of mutual regulation. Which fibroblasts in wound healing role is particularly important. diabetic patients with skin vulnerable to damage, delayed wound healing after injury or nonunion, a clinical solved the difficult and hot. In recent years, the diabetic fibroblast cells as well as changes in fibroblasts of rapid development, the latest study found that diabetes changes of fibroblasts in wound healing in diabetes play an important role in this connection are reviewed. [Keywords:] diabetes mellitus; healing; wound; fibroblasts With the social and economic development around the world, living standards, changes in the diet, increasing pace of life and less stress and more dynamic way of life and many other factors take the global incidence and prevalence of diabetes, the rapid growth of diabetes has become the cancer, cardiovascular disease after the third serious threat to human health from chronic diseases. diabetic patients vulnerable to damage the skin, delayed healing, the formation of refractory ulcer refractory. high incidence of diabetes and its complications in the characteristics of multi- increasingly become a research hotspot. Therefore, the treatment of diabetic ulcers is a clinical one of important issues need to be resolved. With the recent development of molecular biology and other disciplines, the study of diabetic wound healing are becoming increasingly in-depth, fibroblast cells wound healing plays an important role, this article on diabetes wound healing in diabetic fibroblast cells and fibroblasts change are reviewed in order to understand fibroblasts in diabetic wound healing and normal wound healing in different, and for related to basic rese