Olfactory ensheathing cells in the nervous system damage repair of.docVIP

 PAGE \* MERGEFORMAT 15 Olfactory ensheathing cells in the nervous system damage repair of Of: Chen Li-fat, Yuhua Rong Bing positions [Abstract] olfactory ensheathing cells are a special glial cells, is the only applied to the cells after spinal cord injury. Injury repair in the nervous system, olfactory ensheathing cells to improve the injury microenvironment, and promote axonal regeneration, through the glial scar, affinity nerve regeneration of neurons and the role of guidance for nervous system repair, and disease treatment of a broad clinical application. [Keywords:] olfactory ensheathing cells; nerve injury; repair Abstract: Olfactory ensheathing cells are specialized glial cells that have been exclusively used in clinical treatment of spinal cord injury.Olfactory ensheathing cells have many effects on repairing nervous system injury, such as improving lesion micro environment, enhancing axon regeneration, crossing glue scar, affiliating neuron and guiding neural regeneration.Olfactory ensheathing cells have wide clinical perspect in repairing nervous system injury. Keywords:: olfactory ensheathing cells; nervous system injury; repair Early in the 19th century, people have found lower vertebrates such as fish and amphibians can be regenerated peripheral and central nervous system, but the mammals, only the peripheral nerve regeneration after injury, no central nervous system regeneration. Peripheral nervous system (peripheral nervous system, PNS) and central nervous system (central nervous system, CNS) injury is an important difference: PNS extended germination can continue to grow and eventually form functional contact with the target organs, and CNS germination can not continue to grow, then die, fiber degeneration, cell body death. Since the 70s of last century, along with the related disciplines theory and technological progress, and gradually proved that the adult mammalian CNS has a strong plasticity, when the central neurons to in