Omeprazole in the prevention of acute hepatic artery chemoembolization hemorrhagic mucosal lesions.docVIP
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Omeprazole in the prevention of acute hepatic artery chemoembolization hemorrhagic mucosal lesions
Omeprazole in the prevention of acute hepatic artery chemoembolization hemorrhagic mucosal lesions
[Abstract] Objective To observe the TACE omeprazole prevention of acute gastric mucosal lesions after hemorrhage. Methods 46 patients the day after intravenous infusion of omeprazole 40mg, day 1, and set non-Olympic Merah yl group, treatment for 7 days. Results omeprazole group was significantly lower than non-bleeding omeprazole group (8.7% and 27.5%, P lt;0.005. Conclusion of omeprazole on hepatic artery chemoembolization acute gastric mucosal lesion bleeding a good preventive effect.
[Keywords:] omeprazole, hepatic artery chemoembolization, acute gastric mucosal lesion bleeding
Hepatic arterial chemoembolization for hepatocellular carcinoma has become one of the main methods, clinical efficacy, but patients with acute gastric bleeding occur, for which we use omeprazole for prevention of postoperative bleeding acute gastric mucosal lesion good results are reported below.
1 Materials and methods
1.1 General information on all patients are our hospital from January 2006 to July 2008 were treated by primary liver cancer by hepatic artery chemoembolization, a total of 86 cases. Diagnostic Imaging + + by clinical laboratory tests, diagnosed .86 patients were randomly divided into two groups, of which a total of 46 cases of omeprazole group, 38 males, 8 females, aged 33 to 67 years old, no history of chronic liver disease, 10 cases had a history of 36 patients with chronic liver disease . non-omeprazole group, 40 patients, 29 males and 11 females, aged 28 to 70 years old, no history of chronic liver disease in 15 cases, there is a history of 25 patients with chronic liver disease. There was no preoperative upper gastrointestinal endoscopy bleeding and ulcers, platelets, prothrombin time, prothrombin activity comparable.
1.2 Methods omeprazole group began the day after application of omeprazole 40mg intravenous infusion, day 1, plus mucosal protective age
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