On ischemic cerebrovascular disease drug treatment.docVIP

 PAGE \* MERGEFORMAT 14 On ischemic cerebrovascular disease drug treatment [Paper Keywords:] ischemic cerebrovascular disease; drug therapy Abstract: ischemic cerebrovascular disease (ischemic cerebrovascular disease, ICVD) in cerebrovascular disease accounted for 85% [1], whose treatment methods include: causes of treatment and conventional medical treatment (also related to drugs), medication, nerve involvement therapy and stem cell transplantation and so on, but the most common treatment is still the drug treatment. So how rational choice of treatment drugs has become ischemic cerebrovascular disease the focus of discussion. In this paper, ischemic cerebrovascular disease will not go into conventional medical treatment, only drug treatment are summarized as follows: An anti-platelet aggregation drugs For patients with ischemic cerebrovascular disease, we recommend the use of anti-platelet aggregation medication. Anti-platelet aggregation drugs include aspirin (Aspirine), ticlopidine (tidcopidine), clopidogrel and so on. Studies have shown that [2], ischemic stroke, after the initial attack early use of aspirin can significantly reduce the risk of stroke recurrence. 1 European Stroke Prevention Trial (Esps-2, European Stroke Prevention Trial) showed that [3], aspirin and dipyridamole combination of sustained-release agent for more than one drug alone preventive effect better, without increasing the bleeding and other side effects. In addition, China has also carried out 21 106 cases of acute cerebral infarction effects of the aspirin study [2] shows that aspirin can significantly reduce the stroke recurrence rate, without increasing the incidence of hemorrhagic stroke. Adenosine receptor antagonist ticlopidine inhibit adenosine diphosphate main (ADP)-induced platelet aggregation, while at the higher levels of PGI2 can reduce the level of TXA2. Clopidogrel and ticlopidine similar chemical structure, can inhibit ADP-induced plate