On the application of biological activity of lentinan and Research Progress.docVIP

 PAGE \* MERGEFORMAT 11 On the application of biological activity of lentinan and Research Progress Paper Keywords lentinan; biological activity; application; Prospect Abstract lentinan is a complex structure of the polymer with a variety of biological activity, plays an important role in the biological body. Summarizes the biological activity of lentinan and its application at home and abroad and research progress, look forward to the future application of lentinan help. Section Pleurotus mushrooms are mushrooms, edible and medicinal fungi in the world of luxury. It contains a number of effective pharmaceutical component, such as the mushroom polysaccharides, lignin, etc., which leads to widespread attention. In recent years, scholars at home and abroad pharmacological effects of lentinan have done a great deal of research, shiitake mushroom polysaccharide with anti-tumor, blood fat, anti-thrombosis, anti-bacterial, anti-virus effect. A biological activity of lentinan 1.1 The anti-tumor activity of lentinan Mushroom polysaccharide with anti-tumor effect, it has no toxic side effects of chemotherapy drugs. Mushroom polysaccharide into antibody induced a kind of immune activity of cytokines, in which the combined effect of cytokines, immune system enhancement, the tumor cells from the role of defense and destruction [1]. Lentinan by activating macrophages, enhancement of antibody-dependent cell-induced cytotoxicity (ADDC), played by anti-tumor activity; In addition, lentinan also enable expansion of tumor blood vessels and bleeding, leading to tumor hemorrhage and necrosis and complete degradation of [2 ]. This is consistent with the immune surveillance theory point of view, which is that the immune system can kill cancer cells in the immune system to form a powerful cancer prevention and control cells in the immune system. It immunomodulatory effect or influence by a number of key enzymes to increase tumor sensitivity to chemotherapy drugs. Meanwh