On the astragalus Arctium Compatibility on glucose and lipid metabolism and diabetic renal disease of_0.docVIP

 PAGE \* MERGEFORMAT 9 On the astragalus Arctium Compatibility on glucose and lipid metabolism and diabetic renal disease of [Abstract] Objective To observe the astragalus, Arctium Compatibility on glucose and lipid metabolism and diabetic kidney disease. Methods established STZ rat model, Astragalus, Arctium each divided into high, medium and low dose 3, orthogonal design method in accordance with different doses of a combination of fed rats, the first 4,8 weeks, blood glucose, blood lipids, 24 h urinary protein excretion, and renal histopathology. Results Astragalus, Arctium compatibility can be reduced blood glucose, blood lipids, reduced 24 h urinary protein excretion, inhibition of mesangial matrix accumulation. Experiment 4 weeks, mainly to the compatibility of high doses of Arctium, lowering blood glucose and cholesterol is better, the first 8 weeks to the compatibility of Astragalus-based high dose reduced triglycerides, glycosylated hemoglobin, decreased 24 h urine protein and the role of mesangial matrix significantly. Conclusion AM, Arctium compatibility corrects glucose and lipid metabolism disorders of diabetes, reduce kidney disease different stages of the experiment, astragalus, Arctium the role of different doses of compatibility exists. [Keywords:] Astragalus, Arctium, orthogonal design, diabetic rat model Keywords:: Astragalus, Arctium, orthogonal design, diabetic rats model Astragalus, Arctium commonly used to treat diabetes medicine. Astragalus Arctium mixture in reducing the early and mid-term blood glucose in patients with diabetic nephropathy, blood lipids, reduce urinary protein has a certain effect [1]. According to syndrome differentiation point of view, different stages of the disease, Astragalus, Arctium compatibility dose effect may exist in different combinations. In this study, the orthogonal design method, Astragalus, Arctium compatibility according to the different doses in the experiment 4 8 weeks were observed o