Parkinsons urban and rural areas the incidence of brain atrophy in patients with different.docVIP

 PAGE \* MERGEFORMAT 10 Parkinson’s urban and rural areas the incidence of brain atrophy in patients with different Of: construction, SJ Lee Hsiao-Chuan Fa Huang Xiaoyu Xiang CYTOCHEMISTRY [Keywords:] brain atrophy, Parkinson’s disease, risk factors, environmental factors Parkinson’s disease (PD mainly neural basal ganglia disease, is the second most common neurodegenerative disease that affects more than 65 years of age more than 1% of the population (1). PD etiology has not yet understood, may be some environmental factors such as wells water, exposure to pesticides or herbicides, manganese, education, smoking, headaches, positive family history, genetic history and so on. China as a special professional relationship, long-term living in urban and rural living habits, living environment, physical condition showed significantly different characteristics and so on. long-term residents in rural areas, more opportunities for exposure to pesticides, and too few opportunities for urban populations are exposed. PD patients in urban and rural areas the incidence of brain atrophy have different characteristics, the regression analysis of this article . 1 Subjects and methods 1.1 study All the cases were from January 1990 to October 2008 the First Affiliated Hospital of Chongqing Medical University, Department of Neurology, Jiangxi Provincial People’s Hospital and the First Affiliated Hospital of Chongqing Medical University hospital diagnosis of PD, a total of 114 patients, aged 65 years were these early onset cases. for all patients by the residents ask for age, sex, hypertension, diabetes, coronary heart disease, smoking, alcohol consumption, ischemic cerebrovascular disease, PD and other medical history and general physical examination and neurological examination, monitoring blood pressure and blood lipids were recorded. All the cases are of brain MRI scan showed brain atrophy are localized or general, widened sulci, enlarged ventricles and so on