Performance liquid chromatography - tandem mass spectrometry method for simultaneous determination of 16 kinds of toys carcinogenic and allergenic dyes.docVIP

 PAGE \* MERGEFORMAT 18 Performance liquid chromatography - tandem mass spectrometry method for simultaneous determination of 16 kinds of toys carcinogenic and allergenic dyes Study: Birch * Chao Zhang Qiang Ma Ma Micro-week Dongyi Yang Wang Baolin [Abstract] for simultaneous determination of 16 kinds of toys and sensitization carcinogenic dye (acid red 26, basic red 9, Disperse Blue 1, Acid Violet 49, Disperse Blue 3, Solvent Yellow 1, Disperse Blue 106, Disperse Orange 3 , Disperse Yellow 3, Basic Violet 1, Basic Violet 3, Disperse Red 1, Solvent Yellow 3, Disperse Blue 124, Solvent Yellow 2, Disperse Orange 37’s performance liquid chromatography - tandem mass spectrometry analysis. textiles, leather, paper, wood, balloons, modeling clay, stickers, can be in contact with liquid, such as different types of toys materials by ultrasonic extraction, the Waters ACQUITY UPLC BEH C18 column (50 mm × 2.1 mm, 1.7 μm after separation of UPLC / MS / MS multiple reaction monitoring mode .16 qualitative and quantitative analysis of carcinogenic and allergenic dyes and the detection limit of 1.0 ~ 8.0 μg / kg, at 5 ~ 100 μg / kg range of low, medium, high 3 The average recovery of added standard was 81.3% to 98.6%, day precision were less than 11%, inter-day precision were less than 14%. This method is accurate, rapid, sensitive and can be used for the actual inspection of toys. [Keywords:] performance liquid chromatography - tandem mass spectrometry; toys; carcinogenic dye; pulsed dye Abstract A comprehensive analytical method based on ultra performance liquid chromatography tandem mass spectrometry has been developed for the simultaneous determination of 16 carcinogenic and allergenous dyestuffs (acid red 26, basic red 9, disperse blue 1, acid violet 49, disperse blue 3, solvent yellow 1, dispersed blue 106, disperse orange 3, disperse yellow 3, basic violet 1, basic violet 3, disperse red 1, solvent yellow 3, disperse blue 124, solvent yellow 2 and disperse