Perioperative patients with rectal cancer changes in hemorheology.doc

 PAGE \* MERGEFORMAT 16 Perioperative patients with rectal cancer changes in hemorheology [Abstract] Objective: To investigate cancer patients during anesthesia and early postoperative changes in blood rheology. Methods: ASA I a grade Ⅱ patients with rectal cancer radical surgery of 30 patients aged 40 to 60 years, before anesthesia anesthetized and 30min, operation (anesthesia time), 24,48,72 h after cubital vein were collected to detect Hηb, Lηb, ESR, Hct, EAI, EDI, ERI and so on. Results: The comparison with those before anesthesia, anesthesia During Hηb, Lηb, ηr, ηp, Hct, ESR, EAI, ERI were lower, which Hηb, Lηb, ηp, Hct, ESR was significantly reduced compared with those before anesthesia (P lt;0.05 or P lt;0.01); the blood of early postoperative RHEOLOGY gradually increased: (1) Hηb, Lηb, ηr, ηp, ESR, EAI to the time beyond the normal range after 72h; (2) EDI 24h ~ 72h after surgery was significantly lower (P lt;0.05). Conclusions: (1) rectal cancer patients in the anesthesia before surgery obvious changes in blood rheology, showing increased blood viscosity; (2) during anesthesia reduces blood rheology indices, blood viscosity decreases; (3) surgery patients with early stage after whole blood reduced viscosity, erythrocyte aggregation index, whole blood viscosity increased gradually hemorheology, erythrocyte deformation index decreased significantly, to maintain the microcirculation and prevent postoperative thrombosis was negative. [Keywords:] cancer; Hemorheology; anesthesia; perioperative Cancer is a serious common diseases harmful to human health, 60% of cancer patients complicated with thrombosis and hypercoagulable state [1,2]. Blood viscosity increases, leading to microcirculatory disturbances, it is prone to deep vein thrombosis. The of dynamic observation during anesthesia and early postoperative rectal cancer patients Rheology of analysis anesthesia and postoperative blood rheology changes in mechanism, to explore cancer patients during