Pills on the aging kidney intestinal CD4 + T cells CD8 + T cells.doc

 PAGE \* MERGEFORMAT 9 Pills on the aging kidney intestinal CD4 + T cells CD8 + T cells [Abstract] Objective Qi Pill Study on D-galactose induced aging rat intestinal mucosa in CD4 + T cells, CD8 + T cells and to explore the role of anti-aging pill kidney. Methods 30 male Wistar rats were randomly divided into 4, the experimental group (high and low dose group) and model group D-galactose by subcutaneous injection, while the experimental group fed with kidney pills, the control group, model group were given the same amount of normal saline, continuous 42 d, were taken duodenum, jejunum, ileum, immunohistochemistry SP method showed that CD4 + T cells within the mucosa, CD8 + T cells, respectively, within the epithelium and lamina propria of the positive cell count. Results In the model group and control group, the epithelium and lamina propria CD4 + T cells were significantly different (P lt;0.05); high dose or low dose group and control group, the epithelium and lamina propria CD4 + T cells were significantly different (P lt;0.05) ; CD8 + T cells in model group and the experimental group and control group, no significant difference (Pgt; 0.05). Conclusion kidney pills can improve the intestinal mucosa in the aging immune cell function. [Keywords:] kidney pills; aging; rats; CD4 + T cells; CD8 + T cells Human aging is the bottleneck of human dream life of a breakthrough, and its mechanism is very complex. In the ancient medical discourses on the mechanism of aging, kidney, spleen deficiency is a pillar of Chinese medicine theory of aging [1,2], and immune senescence theory is limited by modern medicine Researchers generally agree with [3 5]. Shenqi pill is lt;lt;Golden Chambergt;gt; in the treatment of kidney deficiency syndrome of the classic side, the side next to kidney yang, but in fact from Yin Yang, Yin and Yang make up two-kidney virtual too complex, sufficient strength to Royal evils. In this study, D-galactose (D-gal) of aging rats, observed th