Plus the keel Oyster Bupleurum Decoction on elevated plus-maze behavior of rats.doc

 PAGE \* MERGEFORMAT 8 Plus the keel Oyster Bupleurum Decoction on elevated plus-maze behavior of rats Author: Wang Xun, Sun Fu-jun ZHANG Xi-lin Zhang [Abstract] Objective internationally accepted animal model of anxiety, elevated plus-maze (EPM), from the perspective of behavioral observation of Bupleurum Decoction plus keel Oyster rats anxiolytic effect on the EPM. Method of continuous keel for Oyster Bupleurum Decoction plus 10 d, record the rats OE, OT, CE, CT value and down to explore the frequency of indication of the vitality of the movement in rats. The results of the preparation can significantly reduce the EPM in rats OE% and OT%, lower in rats in an open arm and the central platform area head-dipping frequency and closed arm rearing values; 3 the amount of dose - effect relationship positively correlated. Conclusions Bupleurum Decoction plus keel oyster has a clear anxiolytic effect. [Keywords:] Bupleurum plus keel oyster soup elevated plus-maze animal model of anxiety behavior in rats Abstract: ObjectiveTo observe the effect of anti-anxiety of Chaihu-Longgu Muli decoction on the angle of behavior by adopting the international common used anxiety animal model with the elevated plus-maze test (EPM). MethodsChaihu-Longgu Muli decoction was given to rats for 10 days. OE, OT, CE, CT and head-dipping were recorded.ResultsChaihu-Longgu Muli decoction could reduce the OE and OT percentage obviously, reduce the open arm and central platform’s head-dipping and close arm’s rearing in a dose - dependent manner.ConclusionChaihu-Longgu Muli decoction has the effect of anti-anxiety. Keywords:: Chaihu-Longgu Muli Decoction; EPM; Rat; Behavior Bupleurum plus keel only found in oyster soup ‘of typhoid fever on the ‘107:’ typhoid Bajiu Ri, under the, chest full, trouble panic and negative urine, delirium, not Zhuance who Bupleurum plus oyster soup Lord of the keel. ‘Bupleurum plus keel oyster soup and spirit of the treatment of emotional disorders, related to