Ppatients with acute coronary syndrome selectin platelet glycoproteinb -a and C reactive protein.docVIP
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Ppatients with acute coronary syndrome selectin platelet glycoproteinb -a and C reactive protein
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Ppatients with acute coronary syndrome selectin platelet glycoproteinb /a and C reactive protein
Of: Miao Qing Wu Weili Liang Xue Ling Hao Guozhen Fu Xianghua
[Abstract] patients with acute coronary syndrome (ACS patients with P selectin, platelet glycoprotein b / a receptor and C reactive protein. Methods 59 patients with ACS and stable angina (SA) 19 patients patients, 25 patients with normal coronary angiography as control group. Determination of P selectin, platelet glycoprotein b / a receptor and C-reactive protein (CRP, compared between groups. Results ACS platelet membrane P selectin, platelet glycoprotein IIb / IIIa receptor and C-reactive protein were higher than SA patients (P lt;0.01 and control group (P lt;0.01. Conclusion P selectin, platelet glycoprotein b / a receptor and CRP with or without the crown heart disease and different populations of patients with coronary heart disease severity were significantly different in its clinical testing will help identify and predict vulnerable plaque, vulnerable patients found that, in order to take timely and effective clinical interventions to prevent disease progression, thereby reducing the morbidity of patients and mortality.
[Keywords:] acute coronary syndrome, P selectin, platelet glycoprotein IIb / IIIa receptor, C-reactive protein
Acute coronary syndrome (ACS is a serious hazard to human health of common and frequently occurring, is the highest mortality of cardiovascular disease. The pathogenesis of coronary artery thrombosis secondary to plaque rupture. Numerous studies confirm that inflammation in the arteries the formation of atherosclerosis, the process of evolution and cracking plays an important role (1). P selectin are cell adhesion molecules in the selectin family, is the inflammatory response and platelet activation in one of the most sensitive marker (2 ), platelet glycoprotein b / a receptor activation is a platelet aggregation central link, C-r
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