Radiation treatment of esophageal carcinoma.docVIP

 PAGE \* MERGEFORMAT 3 Radiation treatment of esophageal carcinoma [Keywords:] esophageal cancer; radiation therapy Esophageal cancer is a serious harm our people’s health, one of the ten malignant tumors, radiation therapy in its treatment play a very important role. Radiotherapy for esophageal cancer at home and abroad pay close attention to progress of the study, for us to expand treatment ideas for the benefit of more patients is very useful. 1 on esophageal cancer radiation treatment time  dose Factors Of time - dose factor of esophageal cancer radiation therapy is always the most important aspects of research in recent years, the study of the issue have been gradually beyond the scope of radiation therapy alone. Zhao et al [1] reported esophageal cancer late course accelerated hyperfractionated radiotherapy (LCAF) long-term efficacy results are encouraging. Them to take the first 2 / 3 courses of all patients were conventional radiotherapy, 1.8Gy / d, 5d / week, in the 4 to 5 weeks for 23 minutes irradiation, the dose 41.4Gy; after 1 / 3 of course, using wild shrink irradiated 1.5Gy / times, 2 times / d, twice exposure time interval of not less than 6h, giving a total of 27Gy. The whole course of the total radiation dose of 68.4Gy/41 fractionated / 44d. The authors believe that: LCAF program to the limitations of esophageal squamous cell carcinoma of the local control rate and long-term survival, and RTOG85  01 and 94  05 standard chemotherapy results of a comprehensive treatment program similar, but the program of acute radiation response and late radiation toxicity is more serious cases. The authors also LCAF program plus concurrent chemotherapy for the treatment of esophageal squamous cell carcinoma carried out a Phase Ⅲ clinical study [2], chemotherapy programs: 5  fluorouracil (5  Fu) 600mg / (m2 * d) (Chapter 1 ~ 3d ), cisplatin (DDP) 25mg / (m2 * d) (Chapter 1 ~ 3d), chemotherapy, radiotherapy section 1d from the start, repeat eve