Resorcinol compound tincture preparation and quality control.doc

 PAGE \* MERGEFORMAT 13 Resorcinol compound tincture preparation and quality control 【Abstract】 Objective To develop a treatment of the skin disease psoriasis (hand, foot, tinea corporis) and tincture compound resorcinol and the establishment of quality control methods. Methods based on the compound resorcinol lotion by adding salicylic acid, antioxidant tincture made of sodium sulfite, etc., to study the stability of quality, efficacy observation. Results Resorcinol compound tincture right itch, especially in intractable skin ringworm cure rate 78.8%, with a total effective rate was 96.6%, with a total determination of recovery 100.8%, RSD = 0.48%. Conclusion The compound is superior to compound tincture between the phenol resorcinol lotion; the preparation method is simple, good stability, good curative effect. Keywords: compound resorcinol tincture; Quality Control Skin ringworm (hand, foot, tinea) is a mold (fungi) caused by skin diseases. Salicylic acid has antibacterial, anti-itching of the efficacy, resorcinol, phenol has a role in killing mold, acetone soluble sebum, to enhance drug penetration, joint application, especially for intractable skin ringworm has a good synergistic therapeutic effect, while adding antioxidant sodium bisulfite resolved resorcinol, phenol oxidation in the preparation easy to store in the discoloration of the questions [1]. With resorcinol lotion [2] controlled trials, clinical treatment of 300 cases of skin psoriasis patients, the cure rate by the compound resorcinol lotion 60% to 78.8% in compound tincture resorcinol. An instrument and reagent TJ-328 electro-optical analytical balance (Shanghai Balance Instrument Factory); resorcinol (Shantou Guanghua Chemical Factory); phenol (Tianjin East pharmaceutical); salicylic acid (mixture of Nanchang City Yangtze River Chemical Factory); the rest of are drug supplies or AR. 2 Preparation of compound tincture Resorcinol