Ropivacaine mesylate in epidural anesthesia with bupivacaine in comparison.doc

 PAGE \* MERGEFORMAT 7 Ropivacaine mesylate in epidural anesthesia with bupivacaine in comparison [Abstract] Objective To compare ropivacaine mesylate in epidural anesthesia with bupivacaine, the efficacy and adverse reactions, the differences of the two anesthetics and advantages and disadvantages, choosing the most useful in clinical anesthesia. Methods gynecological laparotomy in our hospital 60 patients were randomly divided into two groups to compare the anesthetic effect and adverse reactions in anesthesia, complications, anesthesia time, and clinician satisfaction. The results of two drugs can be good to meet clinical doctor’s request, but bupivacaine in hemodynamic instability, intraoperative blood pressure decreased significantly, with heart rate and need medical treatment to recover, ropivacaine mesylate hemodynamically stable, with only part of the decreased blood pressure, no drug treatment, the infusion speed can slightly speed up the recovery. ropivacaine mesylate conclusions of low toxicity, clinical adverse reactions, more suitable for clinical application. [Keywords:] mesylate ropivacaine, bupivacaine, epidural anesthesia compared Bupivacaine hydrochloride as long-acting amide local anesthetic, is widely used in epidural anesthesia and postoperative analgesia, the exact effect of clinical anesthesia, but the central nervous system and cardiac toxicity. Ropivacaine mesylate is a domestic New long-acting amide local anesthetic, a longer time than bupivacaine, is a highly efficient and low toxicity of the anesthetic. The study compared surgery with ropivacaine mesylate in epidural anesthesia in the bupivacaine the effectiveness and advantages and disadvantages. 1 Materials and Methods 1.1 General Information Select ASAI ~ II elective gynecological surgery under epidural anesthesia in 60 patients, aged 20 to 60 years old, weighing 40 ~ 70Kg, including hysterectomy in 20 cases, 20 cases of uterine fibroids excavation operation, ect