T lymphocytes of tea polyphenols on human colon cancer cell lines and the impact of SW480.docVIP

 PAGE \* MERGEFORMAT 20 T lymphocytes of tea polyphenols on human colon cancer cell lines and the impact of SW480 Of: Zhuyue Rong, Qiu, Liu Jun rights, Chen revival [Abstract] Objective: To observe the tea polyphenols on ???T cell killing activity of tumor cells and induction of human colon cancer cell lines (SW 480 apoptosis and death. METHODS: In vitro with different concentrations of tea polyphenols induce ???T cells and SW 480 cell lines, and determination of human ???T cells kill tumor activity and tumor cells. with different concentrations of tea polyphenols induced by SW 480 cells, respectively, 4 h, discard the culture medium contains polyphenols and then cultured for 24 h, and then death and apoptosis were measured using ???T cells for the control group. Results: The TP concentration of 350 mg / L, the role of ???T cells significantly increased after 4 h ???T cell-killing activity of tumor cells with no induction group Compared with other concentrations, P lt;0.01, ???T cells by tea polyphenols treated SW 480 cells was also significantly higher killing activity (P lt;0.01. various concentrations of tea polyphenols and SW 480 respectively ???T cells 4 h, then cultured for disposable fluid induced 24 h after death and can induce apoptosis, in the TP concentration of 350 mg / L, 4 h induction time, the most obvious, the same concentration of tea polyphenols induced SW 480 cell death and apoptosis was significantly higher than ???T cell group. Conclusion: TP at a certain concentration can significantly improve ???T killing activity of tumor cells by tea polyphenols treated SW 480 cells more susceptible to cell killing ???T. Tea polyphenol concentration of 350 mg / L when apoptosis induced by SW 480 cells had no effect on human ???T cells. [Keywords] tea polyphenols, ??? cells, SW 480 cell line, anti-tumor activity, apoptosis [Abstract] Objective: To observe cytotoxicity of ???T cell induced by tea polyphenols and the direct effects of tea polyp