To improve the quality of randomized controlled trials of Chinese herbal medicine Ⅱ - the control group design.docVIP

 PAGE \* MERGEFORMAT 24 To improve the quality of randomized controlled trials of Chinese herbal medicine Ⅱ : the control group design Authors: BIAN Zhao-xiang, LI You-ping, Liu Liang, Tai-Xiang Wu, Jiang-Xia Miao [Keywords:] Chinese herbal medicine [Abstract] Objective: how to choose the control group randomized controlled trial design, one of the key links. Through the Cochrane Library published on the herbal treatment of type 2 diabetes systematic review contained in 66 clinical trials designed to evaluate the control group analysis of clinical trials of Chinese herbal medicine to explore how to improve the design quality of the control group. Methods: The literature search published before July 2005 and included in the Cochrane Library of clinical trials, the most systematic evaluation - Chinese herbal medicine treatment of type 2 diabetes systematic review of 66 clinical trials, analysis of randomized controlled trials of Chinese herbal medicine in the control group design the problems. Results: In 66 clinical trials, using control groups, including the placebo group, positive medicine group and blank control group and so on, but in the design of clinical trials, while the control group did not explain reasons for selection; of these 27 clinical trials, using in western medicine and western medicine combined effect of the comparison; 24 clinical trials, efficacy of Chinese herbal medicine and western medicine comparison; five clinical trials, efficacy of Chinese herbal medicine compared with placebo; 3 clinical trials compared Chinese and western medicine and western medicine combined with placebo treatment efficacy; 3 clinical trials compared Chinese and western medicine combined with other traditional Chinese medicine treatment efficacy; traditional Chinese medicine treatment group and blank control group, traditional Chinese medicine combined with western medicine combined placebo treatment compared to placebo were each for a clinical trial ; while a