持续与间断噪声前掩蔽条件下小鼠下丘神经元的不同反应模式.pdfVIP

Acta Physiologica Sinica, ApI诅 25， 2006， 58 (2) : 141-148 14 1 http://www.actaps . Ei4Hi4411W回 Different forward masking pa忱erns ofsustained noise burst and segmental noise burst in the inferior collicular neurons ofthe mouse LI An-An, CHEN Qi-Cai,WU Fei-Jian* School ofLife Sciences, Central China No ,mal University， 附加n 430079, China Abst13Ct: Although th创e has been a growing body oflit町ature showillg the neulal ∞ITelation of f01Wald maskillg caused by a pU le tone maskel in the auditory lleurons, rel阳z刽叩t挝ive few studies ha衍v巳 addt.宫essed， the desclipt挝∞iωO∞n ofhow the fì岛orwa缸1dmasking cωaus钝ed by a noise btu.s especiallya se.quence ofnoωIS优ebur岱古t飞， ♂1S tl百百毫nsfo创11l毡med into lleulonal lepresentation in the central auditory system. Usillg a 1l0ise forward masking paradigm ulld町f1ee field stnuuli ∞nditions， this in vivo study w as devoted to explo1ing it in the inferio1 colliculal (IC) neulons of the mouse (Mus musculus KM). A total of 96 IC neurons were recorded. Rate-intensity fUllctions (RIFs) with and witlhout the p1esentation ofmasker, sustained no时bUlst (SNB) 01 segmentalno时bm臼rst悦t (σSGNB罔)， we 1宦e meωas创u1ed in 51 lleωurons. Wef，缸0αun叫d! 也d1a创t the 1elative maω崎k阳e缸l illt衍enωm时s幻叩i让汹t位1es we盯r何e di削s约由归h仕创如1i MToft也he c∞on电es叩，ponding 阴)1F obeωlle. The masking effect of the SGNB on fuing 1ate in near1y half of neUlons (type 1, 45.10%) was stlong町than that ofthe SNB (P O.OO 1), whe leas in a smaller f1action ofneu1ons (type 田， 17.65%), it was weaker than that oflthe SNB (P0.001). Thele was no significallt diffe1ence in masking effe.ct between the SNB and SGNB ill type II neu1ons (37.25%, P0 , 05). Itlespective oftype 1 01 type m neulons, the inhibiωηeffects of both kinds ofmaskers were all greater at lowe1 probe intens;ities but dec1eased significallt1y w ith the inc1ease of probe intensity (PO.OO 1). lliterestillg1y, as the p 1obe intensity illc1eased, the