Co-expression of vimentin and cytokeratin in bitch mammary gland tumors.docVIP

下载本文档

8
0
约2.17万字
约 9页
2017-05-08 发布于上海
举报
版权申诉

Co-expression of vimentin and cytokeratin in bitch mammary gland tumors.doc

1、原创力文档（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。。
2、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击这里二次下载。
3、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
4、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
5、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
6、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
7、VIP文档为合作方或网友上传，每下载1次，网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档

Co-expression of vimentin and cytokeratin in bitch mammary gland tumors

ActaVeterinaria(Beograd),Vol.57,No.2-3,247-255,2007. DOI:10.2298/AVB0703247J UDK619:618.19-006 CO-EXPRESSIONOFVIMENTINANDCYTOKERATININBITCHMAMMARYGLANDTUMORS JOVI]S,MAGA[VandALEKSI]-KOVA^EVI]SANJA FacultyofVeterinaryMedicine,Belgrade (Received17.December2006) This work presents the results of immunohistochemical studies on the distribution of intermediary filamentous proteins vimentin and cytokeratininbitchmammaryglandtumors,whichhadbeenpreviously classifiedaccordingtothelatestWHO-classification(1999).Theoverall testspecimenincluded45bitchesofdifferentbreedsandage,which resultedindiagnosing27malignantneoplasms,11benignneoplasms, and 3 hyperplastic-dysplastic changes, while 4 test specimens were taken from healthy bitches. The commonest malignant neoplasms were: simple adenocarcinoma (13 cases) and complex adenocarcinoma (7). Among the benign neoplasms the ones that dominatedwerebenignmixedtumors(8cases). Vimentin was expressed on neoplastic proliferative suprabasal myoepithelial cells of simple adenocarcinomas; on resting, spindle- shaped and star-shaped myoepithelial cells of complex adenocarcinomas;oncartilagecellsofcarcinomasinthemixedtumor andbenignmixedtumors;onosteoidcellsofosteosarcoma;andon myofibroblasts of simple adenocarcinomas, complex adenocarcinomas,carcinomasinthemixedtumorandbenignmixed tumors,andconnectivetissuefibresoffibrosarcoma.Theexpressionof cytokeratinwasnoticedoncanalicularandalveolarlumenepitheliumof simple adenocarcinomas, adenocarcinomas; on epithelial cells of carcinomas in the mixed tumor, mutinous complex carcinomas,fibrosarcomaandofosteosarcoma;onrestingandstar- shaped myoepithelial cells of complex adenocarcinomas and carcinomas in the mixed tumor; as well as on spindle-shaped myoepithelial cells of carcinomas in the mixed tumor. Proliferative suprabasalmyoepithelialcellsofsimpleadenocarcinomasshowedthe co-expressionofvimentinandcytokeratin,andsodidtherestingand spindle-shaped myoepithelial cells of complex tubular adenocarc