Correspondence Prostatic sarcoma after treatment for rectal cancer.docVIP

World Journal of Surgical Oncology BioMedCentral Correspondence Open Access Correspondence: Prostatic sarcoma after treatment for rectal cancer Noel J Aherne and Charles M Gillham* Address: Department of Radiation Oncology, St. Lukes Hospital, Dublin 6, Ireland Email: Noel J Aherne - noelaherne@; Charles M Gillham* - cmgillham@ * Corresponding author Published: 17 February 2008 Received: 4 September 2007 Accepted: 17 February 2008 World Journal of Surgical Oncology 2008, 6:20 doi:10.1186/1477-7819-6-20 This article is available from: /content/6/1/20 ? 2008 Aherne and Gillham; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Dear Sirs, Authors contributions NJA: Conception and design, editing of manuscript. The authors Abbas SM, and Hill AG [1] outline their expe- rience of a case of prostatic sarcoma occurring four years post neoadjuvant radiation therapy for primary mid rectal adenocarcinoma. They correctly state that as this second malignancy occurred within the radiation field it meets the criteria for a radiation – induced second malignancy. However, it has been noted that while there is no estab- lished dose response relationship for sarcoma that they are generally felt to occur within the high dose region. A dose of 4500 cGy seems unlikely to lead to sarcoma for- mation within such a short time frame. CMG: preparation of draft manuscript. All authors read and approved final manuscript. References 1. Abbas SM, Hill AG: Prostatic sarcoma after treatment of rectal cancer. World Journal of Surgical Oncology 2007, 5:82. 2. Sexton WJ, Lance RE, Reyes AO, Pisters PW, Tu S, Pisters L: Adult Prostate Sarcoma: The M.D Anderson cancer centre experi- ence. J Urol 2001, 166:521-525. 3. 4. Cheville