Cutaneous Manifestations of Brucellosis.docVIP

Balabanova-Stefanova et al. Cutaneous Manifestations of Brucellosis Macedonian Journal of Medical Sciences. 2010 Sep 15; 3(3):257-262. doi:10.3889/MJMS.1857-5773.2010.0130 Public Health OPEN?ACCESS Cutaneous Manifestations of Brucellosis Margareta Balabanova-Stefanova, Agron Starova, Irina Arsovska-Bezhoska University Clinic of Dermatology, Medical Faculty, Skopje, Republic of Macedonia Abstract Citation: Balabanova-Stefanova M, Starova A, Arsovska-Bezhoska I. Cutaneous Manifestations of Brucellosis. Maced J Med Sci. 2010;3(3):257- 262. doi.10.3889/MJMS.1957-5773.2010.0130. Aim. To present and compare 10-year clinical experience of human brucellosis in Republic of Macedonia with data presented in the literature about the frequency of cutaneous manifestations of brucellosis. To estimate the percent of underdiagnosed / misdiagnosed skin lesions related to brucellosis and to raise awareness of cutaneous manifestations of brucellosis in our clinical practice. Key words: Brucellosis; cutaneous manifesta- tions; pathogenesis; treatment. Methods. Clinical records and experience of the Infectious Diseases Clinic and Dermatology Clinic, Faculty of Medicine, Skopje, and a review of the recent literature data about cutaneous manifestations of brucellosis relevant for dermatologists, infectologists and general practitioners. Correspondence: Balabanova-Stefanova Margareta, MD, PhD, Professor. University Der- matology Clinic, Faculty of Medicine, Ss Cyril and MethodiusUniversity,MKD-1000Skopje,R.Mac- edonia. margareta_bal@ Phone: +389 E-mail: Results. Cutaneous manifestations or complications have been reported rarely, less than 5% (3.8 % - 17 %) in different published studies. A variety of skin lesions have been reported in patients with brucellosis, including rashes (25%), nodules, papules, erythema nodosum (25%), eczematous lesions (12.5%), psoriasiform lesions (12.5%), petechiae, purpura and others. Received: 03-Feb-2010; Revi