Vascular stem cells in diabetic complications evidence for a role in the pathogenesis and the therapeutic promise 英文论文文献.docVIP

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Vascular stem cells in diabetic complications evidence for a role in the pathogenesis and the therapeutic promise 英文论文文献.doc

Vascular stem cells in diabetic complications evidence for a role in the pathogenesis and the therapeutic promise 英文论文文献

KeatsandKhanCardiovascularDiabetology2012,11:37 /content/11/1/37 CARDIO VASCULAR DIABETOLOGY REVIEW OpenAccess Vascularstemcellsindiabeticcomplications: evidenceforaroleinthepathogenesisandthe therapeuticpromise EmilyCKeats1andZiaAKhan1,2,3* Abstract Longstandingdiabetesleadstostructuralandfunctionalalterationsinboththemicro-andthemacro-vasculature. Vascularendothelialcells(ECs)aretheprimarytargetofthehyperglycemia-inducedadverseeffects.Vascularstem cellsthatgiverisetoendothelialprogenitorcells(EPCs)andmesenchymalprogenitorcells(MPCs)representan attractivetargetforcelltherapyfordiabeticpati

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