菊花活性物质及其作用机制研究.docVIP

Botanical Research 植物学研究, 2012, 1, 47-53 /10.12677/br.2012.13008 Published Online October 2012 (/journal/br.html) Research Advance in Active Substance and Mechanism Action of Chrysanthemum morifolium Yau Lam School of Chinese Medicine, The University of Hong Kong, Hong Kong Email: lamyaugmp@.hk Received: Jul. 18 , 2012; revised: Jul. 29 , 2012; accepted: Aug. 1 , 2012 th th st Abstract: Objective: This paper summarizes the progress of medical research on the chemical composition and pharmacological action of Chrysanthemum morifolium. Method: The method relying upon the literature and academic research. Result: Since ancient times, chrysanthemum plant has been used for both pharma- cological and diet purposes. According to the literature, it has been confirmed to compose of a variety of chemical constituents, including essential oil, flavonoid, amino acid, micronutrient, chlorogenic acid, etc. It can also release a broad spectrum of pharmacological reactions, including anti-bacterial, anti-inflammatory, anti-oxidative, vasodilatation, anti-tumor, lowing blood fat and excreting lead. Conclusion: Chrysanthemum contains very high officinal value. There will be a prospect for nurturing larger proportion of chrysanthemum and other species in this kind to explore its greater development potential in future. Keywords: Chrysanthemum morifolium; Chemical Composition; Pharmacological Action 菊花活性物质及其作用机制研究 林 佑 香港大学中医药学院，香港 Email: lamyaugmp@.hk 收稿日期：2012年 7月 18日；修回日期：2012年 7月 29日；录用日期：2012年 8月 1日 摘 要：目的：本文对菊花活性物质及其作用机制研究进行综述。方法：文献学方法。结果：菊花是 自古以来一直常用至今的药食两用植物.根据研究表明具有多种化学成分，包括挥发油、黄酮类化合 物、绿原酸、氨基酸及其它。而且亦具有广谱的药理活性；对于抗菌、抗炎、抗氧化、舒张血管、降 血压、抗肿瘤及驱铅具有较强的制抑性。结论：菊花具有很高的药用价值；大量栽培菊花及其相关品 种具有一定的开发及利用前景。 关键词：菊花；活性成分；药理作用 1.引言 为药食同源的菊类植物已有 300多年的栽培历史。近 年，随着全球性回归自然与中医中药热潮不断涌涨 下，中医中药在世界各地的声誉和影响也越来越大， 特别是中国加入 WTO 以后市场空间的进一步拓展， 相信具有一定的发