Beta-Lactam Antibiotic Resistance among Enterobacter spp. Isolated from Infection in Animals英文文献资料.docVIP

Advances in Microbiology, 2012, 2, 129-137 /10.4236/aim.2012.22018 Published Online June 2012 (http://www.SciRP.org/journal/aim) Beta-Lactam Antibiotic Resistance among Enterobacter spp. Isolated from Infection in Animals Melissa S. Wilberger , Kate E. Anthony , Sasha Rose , Matt McClain , Luiz E. Bermudez 1* 1* 1,2 3 1,2# 1 Department of Biomedical Sciences, College of Veterinary Medicine, Oregon State University, Corvallis, USA Department of Microbiology, College of Science, Oregon State University, Corvallis, USA Information Technology, College of Veterinary Medicine, Oregon State University, Corvallis, USA 2 3 Email: Luiz.Bermudez@ # Received December 31, 2011; revised February 21, 2012; accepted March 7, 2012 ABSTRACT Nosocomial infections are frequent complications of hospitalization, caused by opportunistic pathogens that gain access to hosts undergoing invasive procedures, such as surgery, intubation, and placement of deep vein lines. Nosocomial infections in animal hospitals can infect other animals, as well as be transmitted to human personnel. Enterobacter is a genus of common gram-negative bacteria, which can be associated with antibiotic resistant hospital infections. Because of an outbreak in antibiotic resistance in the genus, we decided to investigate five years of Enterobacter infections in the Large Animal Services of the Lois Bates Acheson Veterinary Teaching Hospital (LBAVTH) at Oregon State Uni- versity. The demographics from 37 Enterobacter-infected patients of the LBAVTH were obtained from charts and ana- lyzed. The identified clusters of infections suggested possible patient-environment sources of infection. The environ- ment of the hospital was sampled in an attempt to determine the source of infection. Although Enterobacter w