Biobanks for Genomics and Genomics for Biobanks英文文献资料.docVIP

ComparativeandFunctionalGenomics CompFunctGenom2003;4 :628–634. PublishedonlineinWileyInterScience().DOI:10.1002/cfg.333 ConferenceReview Biobanksforgenomicsandgenomicsfor biobanks AnneCambon-Thomsen1*,PascalDucournau1,2,Pierre-AntoineGourraud1andDavidPontille1,3 1InsermU558,Epid′emiologieetAnalyses enSant′ePublique: Risques, Maladies Chroniques etHandicaps, Facult′edeM′edecine,37All′eesJ Guesde, 31073Toulouse cedex,France 2FRE2674 CentreInterdisciplinaire deRecherches Urbaines etSociologiques (CIRUS),Universit′eToulouse leMirail(Toulouse II),Maisondela Recherche, 5All′eeAntonioMachado, 31058Toulouse cedex1,France 3UMR5044 Centred’E′tude etdeRecherche Techniques, Organizations, Pouvoirs (CERTOP), Universit′eToulouse leMirail(Toulouse II), MaisondelaRecherche, 5All′eeAntonioMachado, 31058Toulouse cedex1,France *Correspondence to: AnneCambon-Thomsen, Inserm Abstract Biobanks include biological samples andattached databases. Human biobanks occur in research, technological development and medical activities. Population genomics is highly dependent on the availability of large biobanks. Ethical issues must be Handicaps, Facult′edeM′edecine, considered: protecting the rights of those people whose samples or data are in 37All′eesJulesGuesde, F-31073 biobanks (information, autonomy, con?dentiality, protection ofprivate life),assuring U558,Epid′emiologieet Analyses enSant′ePublique: Risques,Maladies Chroniques et Toulouse cedex,France. E-mail:cambon@cict.fr the non-commercial use of human body elements and the optimal use of samples and data. They balance other issues, such as protecting the rights of researchers and companies, allowing long-term use of biobanks while detailed information on future uses is not available. At the level of populations, the traditional form of informed consent is challenged. Other dimensions relate to the rights of a group as such, in addition to individual rights. Conditions of return of results and/or bene?t to a population nee