Cardiac Function in 7-8-Year-Old Offspring of Women with Type 1 Diabetes英文文献资料.docVIP

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Cardiac Function in 7-8-Year-Old Offspring of Women with Type 1 Diabetes英文文献资料.doc

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Cardiac Function in 7-8-Year-Old Offspring of Women with Type 1 Diabetes英文文献资料

HindawiPublishingCorporation ExperimentalDiabetesResearch Volume2011,ArticleID564316,7pages doi:10.1155/2011/564316 ClinicalStudy CardiacFunctionin7-8-Year-OldOffspringof WomenwithType1Diabetes MaartenRijpert, CobiJ.Heijnen, 1 JohannesM.P.J.Breur, IngeM.Evers, HaroldW.deValk, 2 2 3 4 1 FolkertJ.Meijboom, andGerardH.A.Visser 1 1 DepartmentofPediatrics,WilhelminaChildren’sHospital,UniversityMedicalCenterUtrecht,P.O.Box85090, 3508ABUtrecht,TheNetherlands 2 DepartmentofPediatricCardiology,WilhelminaChildren’sHospital,UniversityMedicalCenterUtrecht,P.O.Box85090, 3508ABUtrecht,TheNetherlands 3 4 DepartmentofObstetricsandGynecology,MeanderMedicalCenter,P.O.Box1502,3800BMAmersfoort,TheNetherlands DepartmentofInternalMedicine,UniversityMedicalCenterUtrecht,P.O.Box85500,3508GAUtrecht,TheNetherlands CorrespondenceshouldbeaddressedtoMaartenRijpert,m.rijpert@umcutrecht.nl Received21May2011;Revised17August2011;Accepted29August2011 AcademicEditor:BarbaraAlexander Copyright?2011MaartenRijpertetal. This is an open access article distributed under the Creative Commons Attribution License,whichpermitsunrestricteduse,distribution,andreproductioninanymedium,providedtheoriginalworkisproperly cited. O?springoftype1diabeticmothers(ODMs)areatriskofshort-termandlong-termcomplications,suchasneonatalmacrosomia (birthweight90thpercentile),hypertrophiccardiomyopathy,andcardiovascularmorbidityinlaterlife.However,nostudies havebeenperformedregardingcardiacoutcome.Inthisstudy,weinvestigatedcardiacdimensionsandfunctionin30ODMsat7- 8yearsofageinrelationtoneonatalmacrosomiaandmaternalglycemiccontrolduringpregnancyandcomparedthesewiththose inacontrolgroupof30childrenofnondiabeticwomen.Wefoundthatcardiacdimensionsandsystolicanddiastolicfunction parametersinODMswerecomparablewiththoseincontrols.Neonatalmacrosomiaandpoorermaternalglycemiccontrolduring pregnancywerenotrelatedtoworsecardiacoutcomeinODM.Weconcludethatcardiacfunctionat7-8yearsofageino?spring ofwomenwithty