Corticosteroid-Induced Multifocal and Extensive Lipomatosis A Case Report英文文献资料.docVIP

Open Journal of Pathology, 2011, 1, 1-3 doi:10.4236/ojpathology.2011.11001 Published Online October 2011 (http://www.SciRP.org/journal/ojpathology) Corticosteroid-Induced Multifocal and Extensive Lipomatosis: A Case Report Ilham Bouaddi , Hanan Rkain , Fadoua Allali , Nazik Allali , Najia Hajjaj-Hassouni 1 1 1 2 1 1 2 Department of Rheumatology B, El Ayachi Hospital, Rabat-Salé, Morocco; Department of Radiology, Avicenne Hospital, Rabat-Salé, Morocco. Email: drbouaddilham@yahoo.fr Received September 10 , 2011; revised October 12 , 2011; accepted October 23 , 2011. th th rd ABSTRACT Introduction: Corticosteroid-induced lipomatosis are uncommon situation. We report a case of an extensive lipomato- sis in a rheumatoid arthritis patient, who received a long term steroid therapy. Case report: A 49-year-old rheumatoid arthritis woman, who received for two years a mean dose of 15 mg/ day of prednisone equivalent, was admitted to the hospital for a six months history of progressive abdominal distension and dyspnea. Physical exam revealed typical symptoms of Cushing’s syndrome and an important increase of abdominal volume. Lipomatosis diagnosis with mesen- teric, mediastinal, retroperitoneal and epidural localizations, was rapidly confirmed by sonography and computed to- mography (CT) exams. Management was based on corticosteroid reduction as well as use of hygiene and dietary meas- ures. Therapeutic efficacy was noted on a clinical basis within one year. Discussion: