妊娠期高血压对新生儿血清脂联素水平的影响.docVIP

妊娠期高血压对新生儿血清脂联素水平的影响 　　 【摘要】 目的 探讨妊娠期高血压对新生儿血清脂联素水平的影响。 　　方法 将妊娠高血压综合征孕母所生的58例新生儿随机分为三组，妊娠期高血压组22例，子痫前期轻度组20例，子痫前期重度组16例，并选择非妊娠高血压综合征孕母所生的20例新生儿作为健康对照组。比较四组新生儿血清脂联素水平，以及脂联素与胎儿出生体质量和体质指数(BMI)的关系。结果 四组新生儿的脂联素、体质量及BMI均不同（P＜0.05），其中，子痫前期轻度组和子痫前期重度组新生儿的脂联素水平显著低于健康对照组（P＜0.05），子痫前期重度组新生儿的脂联素水平低于子痫前期轻度组（P＜0.05）。子痫前期重度组新生儿的出生体质量及BMI均显著低于健康对照组（P＜0.05）。血清脂联素与出生体质量和BMI均为正相关关系（P＜0.05）。结论 随着妊高征程度的加重，脂联素的水平不断降低，脂联素可作为衡量胎儿生长发育状态的重要指标之一。 　　 【关键词】 妊娠高血压综合征；新生儿；血清；脂联素 　　 文章编号：1003-1383(2011)06-0705-03 中图分类号：R 722.1 文献标识码：A 　　doi:10.3969/j.issn.1003-1383.2011.06.007 　　 　　The influence of gestational hypertension on the serum adiponectin level of the neonatus 　　LU Caixia, LIChune, WANG Hailan, ZHAO Jianqin 　　（Department of Pediatrics, Minhang District Central Hospital, Shanghai 201199） 　　 【Abstract】 Objective Discuss the influence gestational hypertension on the serum adiponectin level of the neonatus. 　　Methods 58 newborns whose mothers had hypertension during pregnancy were divided into 3 groups: the gestational hypertension group(22 cases),the light preeclampsia group(20cases), the serious preeclampsia group(16cases). And 20 newborns whose mothers are healthy were chosen as the normal control group. Compare newbornsadiponectin level,and the relationship of adiponectin level and the fetal birth weight and BMI. 　　Results Newbornsadiponectin level, fetal birth weight and BMI of the four groups are different from one another（P＜0.05）. Newbornsadiponectin level of the light preeclampsia group and the serious preeclampsia group was significantly lower than that of control group（P＜0.05）.And newbornsadiponectin level of the serious preeclampsia group was lower than that of the light preeclampsia group（P＜0.05）.The fetal birth weight and BMI of the serious preeclampsia group were significantly lower than those of the normal control group（P＜0.05）.Serum adiponectin,VLBWI and BMI are all positively correlated（P＜0.05）. 　　Conclusion The adiponectin levels gradually decrease along wi