Auditory Development between 7 and 11 Years An Event-Related Potential (ERP) Study 英文参考文献.docVIP

AuditoryDevelopmentbetween7and11Years:An Event-RelatedPotential(ERP)Study DorothyV.M.Bishop1,3*,MikeAnderson1,4,CorinneReid2,4,AllisonM.Fox1,4 1School of Psychology, University of Western Australia, Perth, Australia, 2School of Psychology, Murdoch University, Perth, Australia, 3Department of Experimental Psychology,UniversityofOxford,Oxford,UnitedKingdom,4NeurocognitiveDevelopmentUnit,UniversityofWesternAustralia,Perth,Australia Abstract Background: There is considerable uncertainty about the time-course of central auditory maturation. On some indices, children appear to have adult-like competence by school age, whereas for other measures development follows a protractedcourse. Methodology: Westudiedauditorydevelopmentusingauditoryevent-relatedpotentials(ERPs)elicitedbytonesin105 children on two occasions two years apart. Just over half of the children were 7 years initially and 9 years at follow-up, whereas the remainder were 9 years initially and 11 years at follow-up. We used conventional analysis of peaks in the auditoryERP,independentcomponentanalysis,andtime-frequencyanalysis. Principal Findings: We demonstrated maturational changes in the auditory ERP between 7 and 11 years, both using conventionalpeakmeasurements,andtime-frequencyanalysis.Thedevelopmentaltrajectorywasdifferentfortemporalvs. fronto-centralelectrodesites.Temporalelectrodesitesshowedstronglateralisationofresponsesandnoincreaseoflow- frequency phase-resetting with age, whereas responses recordedfrom fronto-central electrode siteswere notlateralised and showed progressive change with age. Fronto-central vs. temporal electrode sites also mapped onto independent componentswithdifferentlyorienteddipolesourcesinauditorycortex.Aglobalmeasureofwaveformshapeprovedtobe themosteffectivemethodfordistinguishingagebands. Conclusions/Significance: Theresultssupportedtheideathatdifferentcorticalregionsmatureatdifferentrates.TheICC measureisproposedasthebestmeasureof‘auditoryERPage’. Citation:BishopDVM,Anders