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Genome-Wide Scan Identifies Variant in TNFSF13 Associated with Serum IgM in a Healthy Chinese Male Population 英文参考文献.docVIP

Genome-Wide Scan Identifies Variant in TNFSF13 Associated with Serum IgM in a Healthy Chinese Male Population 英文参考文献.doc

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Genome-Wide Scan Identifies Variant in TNFSF13 Associated with Serum IgM in a Healthy Chinese Male Population 英文参考文献

Genome-WideScanIdentifiesVariantinTNFSF13 AssociatedwithSerumIgMinaHealthyChineseMale Population MingYang1.,YongmingWu1,3.,YanmeiLu1.,ChangyuanLiu1.,JielinSun2,MingLiao1,3,MinQin1, LinjianMo1,3,YongGao1,3,ZhengLu1,3,ChunleiWu1,3,YoujieZhang1,3,HaiyingZhang1,4,XueQin1,5 YanlingHu1,6,ShijunZhang1,7,JianlingLi1,8,MinDong1,S.LillyZheng2,JianfengXu2,9,10,11, , XiaoboYang1,4*,AihuaTan1,12*,ZengnanMo1,3 * 1CenterforGenomicandPersonalizedMedicine,TheFirstAffiliatedHospitalofGuangxiMedicalUniversity,Nanning,Guangxi,People’sRepublicofChina,2Centerfor CancerGenomics,WakeForestUniversitySchoolofMedicine,Winston-Salem,NorthCarolina,UnitedStatesofAmerica,3InstituteofUrologyandNephrology,theFirst AffiliatedHospitalofGuangxiMedicalUniversity,Nanning,Guangxi,People’sRepublicofChina,4DepartmentofOccupationalHealthandEnvironmentalHealth,Guangxi MedicalUniversity,Nanning,Guangxi,People’sRepublicofChina,5DepartmentofClinicalLaboratory,theFirstAffiliatedHospitalofGuangxiMedicalUniversity,Nanning, Guangxi,People’sRepublicofChina,6MedicalScientificResearchCenter,GuangxiMedicalUniversity,Nanning,Guangxi,People’sRepublicofChina,7Departmentof Pharmacology,GuangxiMedicalUniversity,Nanning,Guangxi,People’sRepublicofChina,8InstituteofCardiovascularDisease,theFirstAffiliatedHospitalofGuangxi MedicalUniversity,Nanning,Guangxi,People’sRepublicofChina,9CenterforGeneticEpidemiology,VanAndelResearchInstitute,GrandRapids,Michigan,UnitedStates ofAmerica,10Fudan-VARICenterforGeneticEpidemiology,FudanUniversity,Shanghai,People’sRepublicofChina,11FudanUniversityInstituteofUrology,Huashan Hospital,Shanghai,People’sRepublicofChina,12DepartmentofChemotherapy,theAffiliatedTumorHospitalofGuangxiMedicalUniversity,Nanning,Guangxi,People’s RepublicofChina Abstract IgMprovidesafirstlineofdefenseduringmicrobialinfections.SerumIgMlevelsaredetectedroutinelyinclinicalpractice. And IgM is a genetically complex trait. We conducted a two-stage genome-wide association study (GWAS) to identify geneticvariantsaffectingseru

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