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Off-label indications for atypical antipsychotics A systematic review 英文参考文献
Annals of General Hospital
Psychiatry
BioMedCentral
Review
Open Access
Off-label indications for atypical antipsychotics: A systematic review
Konstantinos N Fountoulakis*, Ioannis Nimatoudis, Apostolos Iacovides
and George Kaprinis
Address: 3rd Department of Psychiatry, Aristotle University of Thessaloniki Greece
Email: Konstantinos N Fountoulakis* - kfount@med.auth.gr; Ioannis Nimatoudis - nimatoud@med.auth.gr;
Apostolos Iacovides - iacovid@med.auth.gr; George Kaprinis - kaprinis@med.auth.gr
* Corresponding author
Published: 18 February 2004
Received: 30 January 2004
Accepted: 18 February 2004
Annals of General Hospital Psychiatry 2004, 3:4
This article is available from: /content/3/1/4
? 2004 Fountoulakis et al; licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in
all media for any purpose, provided this notice is preserved along with the articles original URL.
AtypicalTouretteantipsychoticsoff-labels syndromeOCD prescriptionpharmacotherapydepressionpersonality disordersstutteringpervasive developmental disorder-
Abstract
Introduction: With the introduction of newer atypical antipsychotic agents, a question emerged,
concerning their use as complementary pharmacotherapy or even as monotherapy in mental
disorders other than psychosis.
Material and method: MEDLINE was searched with the combination of each one of the key
words: risperidone, olanzapine and quetiapine with key words that refered to every DSM-IV
diagnosis other than schizophrenia and other psychotic disorders, bipolar disorder and dementia
and memory disorders. All papers were scored on the basis of the JADAD index.
Results: The search returned 483 papers. The selection process restricted the sample to 59
papers concerning Risperidone, 37 concerning Olanzapine and 4 concerning Quetiapine (100 in
total). Ten papers (7 concerning Risperidone and
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