On Propagation of Excitation Waves in Moving Media The FitzHugh-Nagumo Model 英文参考文献.docVIP

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On Propagation of Excitation Waves in Moving Media The FitzHugh-Nagumo Model 英文参考文献.doc

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On Propagation of Excitation Waves in Moving Media The FitzHugh-Nagumo Model 英文参考文献

OnPropagationofExcitationWavesinMovingMedia: TheFitzHugh-NagumoModel ElenaA.Ermakova1,EmmanuilE.Shnol2,3,MikhailA.Panteleev4,5,AndreyA.Butylin6,VitalyVolpert7, FazoilI.Ataullakhanov4,5,6 * 1SemenovInstituteofChemicalPhysics,RussianAcademyofSciences,Moscow,Russia,2InstituteofMathematicalProblemsofBiology,RussianAcademyofSciences, Pushchino,MoscowRegion,Russia,3PushchinoStateUniversity,Pushchino,MoscowRegion,Russia,4NationalResearchCenterforHematology,RussianAcademyof MedicalSciences,Moscow,Russia,5CenterforTheoreticalProblemsofPhysico-ChemicalPharmacology,RussianAcademyofSciences,Moscow,Russia,6Departmentof Physics,MoscowStateUniversity,Moscow,Russia,7InstituteofMathematics,UMR5208CNRS,UniversiteLyon1,Villeurbanne,France Abstract Background: Existence of flows and convection is an essential and integral feature of many excitable media with wave propagationmodes,suchasbloodcoagulationorbioreactors. Methods/Results:Here,propagationoftwo-dimensionalwavesisstudiedinparabolicchannelflowofexcitablemediumof theFitzHugh-Nagumotype.Evenifthestreamvelocityishundredsoftimeshigherthatthewavevelocityinmotionless medium(w),steadypropagationofanexcitationwaveiseventuallyestablished.Athighstreamvelocities,thewavedoes notspanthechannelfromwalltowall,formingisolatedexcitedregions,whichwecalled‘‘restrictons’’.Theyareespecially easy toobserve when the modelparameters areclose tocritical ones,at which waves disappear in stillmedium.In the subcriticalregionofparameters,asufficientlyfaststreamcanresultinthesurvivalofexcitationmoving,asarule,inthe form of ‘‘restrictons’’. For downstream excitation waves, the axial portion of the channel is the most important one in determiningtheirbehavior.Forupstreamwaves,themostimportantregionofthechannelisthenear-wallboundarylayers. Therolesoftransversaldiffusion,andofapproximatesimilaritywithrespecttostreamvelocityarediscussed. Conclusions:Thesefindingsclarifymechanismsofwavepropagationandsurvivalinflow. Citation:ErmakovaEA,ShnolEE,PanteleevMA,Butylin