Public health guidance on cardiovascular benefits and risks related to fish consumption 英文参考文献.docVIP

Environmental Health BioMedCentral Commentary Open Access Public health guidance on cardiovascular benefits and risks related to fish consumption Alan H Stern1,2 Address: 1Division of Science, Research and Technology, New Jersey Department of Environmental Protection, 401 E. State St., Trenton, NJ 08625, USA and 2Department of Environmental and Occupational Health, University of Medicine and Dentistry of New Jersey – School of Public Health, 683 Hoes Lane West, P.O. Box 9, Piscataway, NJ 08854, USA Email: Alan H Stern - Alan.Stern@dep.state.nj.us Published: 23 October 2007 Received: 19 June 2007 Accepted: 23 October 2007 Environmental Health 2007, 6:31 doi:10.1186/1476-069X-6-31 This article is available from: /content/6/1/31 ? 2007 Stern; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Historically, concerns with fish consumption have addressed risks from contaminants (e.g., methylmercury (MeHg), and PCBs). More recently public health concerns have widened in appreciation of the specific benefits of fish consumption such as those arising from polyunsaturated fatty acids (PUFAs) in fish oil. Fish contains varying levels of PUFAs and MeHg. Since both address the same health outcomes (in opposite directions) and occur together in fish, great care must be exercised in providing public health guidance. Mozaffarian and Rimm in a recent article (JAMA. 2006, 296:1885–99) have made a strong case for the beneficial effects of PUFAs in reducing the risk of coronary heart disease, but at the same time, have also broadly discounted the increased risks of coronary heart disease posed by MeHg in fish, stating that ... among adults... the benefits of fish intake exceed the potentia