Rationales, design and recruitment for the Elfe longitudinal study 英文参考文献.docVIP

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Rationales, design and recruitment for the Elfe longitudinal study 英文参考文献.doc

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Rationales, design and recruitment for the Elfe longitudinal study 英文参考文献

BMC Pediatrics BioMedCentral Study protocol Open Access Rationales, design and recruitment for the Elfe longitudinal study Stéphanie Vandentorren*1, Corinne Bois2, Claudine Pirus2, Hélène Sarter1, Georges Salines1, Henri Leridon2,3 and the Elfe team Address: 1Département santé environnement, Institut de veille sanitaire, Saint Maurice, France, 2Institut National des études démographiques, Paris, France and 3U822 Epidémiologie, Démographie et Sciences Sociales, INSERM, Le Kremlin-Bicêtre, France Email: Stéphanie Vandentorren* - s.vandentorren@invs.sante.fr; Corinne Bois - corinne.bois@ined.fr; Claudine Pirus - claudine.pirus@insee.fr; Hélène Sarter - h.sarter@invs.sante.fr; Georges Salines - g.salines@invs.sante.fr; Henri Leridon - leridon@ined.fr; the Elfe team - bureau- elfe@ined.fr * Corresponding author Published: 21 September 2009 Received: 25 July 2009 Accepted: 21 September 2009 BMC Pediatrics 2009, 9:58 doi:10.1186/1471-2431-9-58 This article is available from: /1471-2431/9/58 ? 2009 Vandentorren et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: Many factors act simultaneously in childhood to influence health status, life chances and well being, including pre-birth influences, the environmental pollutants of early life, health status but also the social influences of family and school. A cohort study is needed to disentangle these influences and explore attribution. Methods: Elfe will be a nationally representative cohort of 20 000 children followed from birth to adulthood using a multidisciplinary approach. The cohort will be based on the INSEE Permanent Demographic Panel (EDP) established using census data and civil records. The sample size has been defined in order to match