Reasons for Receiving or Not Receiving HPV Vaccination in Primary Schoolgirls in Tanzania A Case Control Study 英文参考文献.docVIP
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Reasons for Receiving or Not Receiving HPV Vaccination in Primary Schoolgirls in Tanzania A Case Control Study 英文参考文献
ReasonsforReceivingorNotReceivingHPVVaccination
inPrimarySchoolgirlsinTanzania:ACaseControlStudy
DeborahWatson-Jones1,2*,KeithTomlin1,PieterRemes2,3,KathyBaisley1,RizikiPonsiano2,
SelephinaSoteli2,SilviadeSanjose′4,5,JohnChangalucha6,SaidiKapiga1,2,RichardJ.Hayes1
1London School of Hygiene and Tropical Medicine, London, United Kingdom, 2Mwanza Intervention Trials Unit, National Institute for Medical Research, Mwanza,
Tanzania,3MedicalResearchCouncil Social PublicHealth Sciences Unit,Glasgow, United Kingdom, 4Unit ofInfections andCancer,Cancer Epidemiology Research
Programme,l’Institutd’Investigacio′ Biome`dica deBellvitge,InstitutCatala` d’Oncologia,Barcelona,Spain,5CIBEREpidemiologia,ySaludPublica,Barcelona,Spain,6The
NationalInstituteforMedicalResearch,Mwanza,Tanzania
Abstract
Background: There are few data on factors influencing human papillomavirus (HPV) vaccination uptake in sub-Saharan
Africa.Weexaminedthecharacteristicsofreceiversandnon-receiversofHPVvaccinationinTanzaniaandidentifiedreasons
fornotreceivingthevaccine.
Methods: We conducted a case control study of HPV vaccine receivers and non-receivers within a phase IV cluster-
randomisedtrialofHPVvaccinationin134primaryschoolsinTanzania.Girlswhofailedtoreceivevaccine(pupilcases)and
theirparents/guardians(adultcases)andgirlswhoreceiveddose1(pupilcontrols)ofthequadrivalentvaccine(GardasilTM
)
and their parents/guardians (adult controls) were enrolled from 39 schools in a 1:1 ratio and interviewed about cervical
cancer,HPVvaccineknowledgeandreasonswhytheymighthavereceivedornotreceivedthevaccine.Conditionallogistic
regressionwasusedtodeterminefactorsindependentlyassociatedwithnotreceivingHPVvaccine.
Results:Weinterviewed159pupil/adultcasesand245pupil/adultcontrols.Adult-factorsindependentlyassociatedwitha
daughterbeingacasewereolderage,owningfewerhouseholditems,notattendingaschoolmeetingaboutHPVvaccine,
and not knowing anyone with cancer. Pupil-factors for being a case included having a non-positive opinio
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