Recombination and base composition the case of the highly self-fertilizing plant Arabidopsis thaliana 英文参考文献.docVIP

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Recombination and base composition the case of the highly self-fertilizing plant Arabidopsis thaliana 英文参考文献.doc

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Recombination and base composition the case of the highly self-fertilizing plant Arabidopsis thaliana 英文参考文献

Open Access Re rch 2004MaraisetVoal.lumesea5, Issue 7, Article R45 Recombination and base composition: the case of the highly self-fertilizing plant Arabidopsis thaliana G Marais*, B Charlesworth* and SI Wright*? Addresses: *Institute of Cell, Animal and Population Biology, University of Edinburgh, EH9 3JT Edinburgh, UK. ?Current address: Department of Biology, York University, 4700 Keele St, Toronto, Ontario M3J 1P3, Canada. Correspondence: SI Wright. E-mail: stephenw@yorku.ca Published: 14 June 2004 Received: 26 March 2004 Revised: 26 April 2004 Accepted: 30 April 2004 Genome Biology 2004, 5:R45 The electronic version of this article is the complete one and can be found online at /2004/5/7/R45 ? 2004 Marais et al.; licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the articles original URL. RecombinationoecifrpfgesacsRntuiiavzcteahe,tsaisoosonftrihinetactoandAeimrtrsmabbibasesinindofalofutpbieocomposition:sanniscseectachoonanmlvigaapenronyasoiamt/mitheoietonon,,rDcaseghgNgoaenwAnieofzorvaemetthepirioe,cnahrthighlyesedthgeeoirnoounszlidsytself-fertilizingygibn,oeisneigutryrkeoiaasnrteylsyxoizprteee,sdce,planttuvaecodnelddtuo.ttArabidopsisihbo/ienspsaitsrryobrnealgitleeyvsreaethalianadndtoducghaveeednaenomajordrdrecr.oImeffectsnbhiingahtlionyonsetheirwlfi-lflebrgenomeetilizingmuch spe-less Abstract Background: Rates of recombination can vary among genomic regions in eukaryotes, and this is believed to have major effects on their genome organization in terms of base composition, DNA repeat density, intron size, evolutionary rates and gene order. In highly self-fertilizing species such as Arabidopsis thaliana, however, heterozygosity is expected to be strongly reduced and recombination will be much less effective, so that its influence on genome organization should be greatly