Removing celiac disease-related gluten proteins from bread wheat while retaining technological properties a study with Chinese Spring deletion lines 英文参考文献.docVIP

Removing celiac disease-related gluten proteins from bread wheat while retaining technological properties a study with Chinese Spring deletion lines 英文参考文献.doc

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Removing celiac disease-related gluten proteins from bread wheat while retaining technological properties a study with Chinese Spring deletion lines 英文参考文献

BMC Plant Biology BioMedCentral Research article Open Access Removing celiac disease-related gluten proteins from bread wheat while retaining technological properties: a study with Chinese Spring deletion lines Hetty C van den Broeck*?1, Teun WJM van Herpen?1,2,3, Cees Schuit1, Elma MJ Salentijn1, Liesbeth Dekking4,5, Dirk Bosch1, Rob J Hamer2, Marinus JM Smulders1,3, Ludovicus JWJ Gilissen1,3 and Ingrid M van der Meer1,3 Address: 1Plant Research International, Wageningen UR, PO Box 16, NL-6700 AA Wageningen, The Netherlands, 2Laboratory of Food Chemistry, Wageningen UR, PO Box 8129, NL-6700 EV Wageningen, The Netherlands, 3Allergy Consortium Wageningen, PO Box 16, NL-6700 AA Wageningen, The Netherlands, 4Leiden University Medical Center, PO Box 9600, NL-2300 RC Leiden, The Netherlands and 5Dynomics BV, Erasmus Medical Centre, Department of Immunology, PO Box 82, NL-1400 AB Bussum, The Netherlands Email: Hetty C van den Broeck* - hetty.busink@wur.nl; Teun WJM van Herpen - teun.vanherpen@wur.nl; Cees Schuit - ceesschuit@bejo.nl; Elma MJ Salentijn - elma.salentijn@wur.nl; Liesbeth Dekking - e.dekking@erasmusmc.nl; Dirk Bosch - dirk.bosch@wur.nl; Rob J Hamer - hamer@tifn.nl; Marinus JM Smulders - rene.smulders@wur.nl; Ludovicus JWJ Gilissen - luud.gilissen@wur.nl; Ingrid M van der Meer - ingrid.vandermeer@wur.nl * Corresponding author ?Equal contributors Published: 7 April 2009 Received: 5 November 2008 Accepted: 7 April 2009 BMC Plant Biology 2009, 9:41 doi:10.1186/1471-2229-9-41 This article is available from: /1471-2229/9/41 ? 2009 Broeck et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: Gluten proteins can induce celiac disease (CD) in genetically susceptible individuals. In CD patients gluten-

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