Retroviral rebound syndrome after treatment discontinuation in a 15 year old girl with HIV attracted through mother-to-child transmission case report 英文参考文献.docVIP

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Retroviral rebound syndrome after treatment discontinuation in a 15 year old girl with HIV attracted through mother-to-child transmission case report 英文参考文献.doc

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Retroviral rebound syndrome after treatment discontinuation in a 15 year old girl with HIV attracted through mother-to-child transmission case report 英文参考文献

AIDS Research and Therapy BioMedCentral Case report Open Access Retroviral rebound syndrome after treatment discontinuation in a 15 year old girl with HIV attracted through mother-to-child transmission: case report Vanda Friman and Magnus Gisslén* Address: Department of Infectious Diseases, the Sahlgrenska Academy at G?teborg University, Sweden Email: Vanda Friman - vanda.friman@infect.gu.se; Magnus Gisslén* - magnus.gisslen@infect.gu.se * Corresponding author Published: 23 February 2007 Received: 9 January 2007 Accepted: 23 February 2007 AIDS Research and Therapy 2007, 4:3 doi:10.1186/1742-6405-4-3 This article is available from: /content/4/1/3 ? 2007 Friman and Gisslén; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract A case of a 15 year old girl with retroviral rebound syndrome after discontinuation of highly active antiretroviral treatment (HAART) due to side effects is presented. The patient was transmitted with HIV at birth by her mother. She had recovered from severe AIDS after HAART was initiated five years earlier. This is the first case reported in the literature of retroviral rebound syndrome in a vertically transmitted HIV-infected patient. Introduction drome after cessation of highly active antiretroviral treat- ment (HAART) in a girl infected with HIV since birth via vertical transmission. Primary acute retroviral syndrome develop in more than 50% of patients infected with HIV [1,2] and more com- monly when HIV is sexually transmitted than intrave- nously [3]. Acute retroviral syndrome has also been reported in children infected through breastfeeding [4], but there are no reports so far describing a similar sero- conversion illness in children infecte